What we all know is obesity is one of the main risk factors for a number of cancers. Obesity has long been "crowned" as a trigger for breast cancer risk in menopausal women. Even so, a recent international study revealed that the risk of breast cancer actually decreased in obese young women. Why is that?
Obese menopausal women are more prone to breast cancer
The accumulation of excessive fat in the body due to obesity, especially abdominal fat, will force the body to produce the hormone estrogen outside the normal range. Excessive levels of estrogen hormone in fact have long been associated as a trigger for breast cancer. In addition, extra fat cells can trigger long-term inflammation in the body.
However, this risk is reported to be higher in obese women who are in menopause. During menopause itself, without any risk factors for obesity the body will naturally produce more estrogen.
That's why women who are overweight and obese (BMI higher than 25) have a higher risk of breast cancer after menopause than women who have a healthy weight. healthy weight. Being overweight can also increase the risk of breast cancer recurrence in cancer survivors. Chronic inflammation has been associated with a higher risk of breast cancer recurrence.
Then, why does obesity actually reduce the risk of breast cancer in young women?
In contrast to what we have known, recent research collaborations between The Premenopausal Breast Cancer Collaborative Group and International Cancer Research have found that obesity lowers the risk of breast cancer in women who just want menopause (perimenopause). The study was published in the journal JAMA Oncology after observing the risk of breast cancer in more than 700 thousand women aged less than 55 years.
Researchers report that women with a high BMI score (indicating being overweight or even obese) but not yet entering menopause have a lower risk of developing breast cancer. They also found that the risk of breast cancer in young women with normal weight remained lower than postmenopausal women
"We saw when the BMI score rose, the risk of cancer declined," said Nichols, an assistant lecturer at the UNC Gillings School of Global Public Health who was involved in the research.
Each increase in 5 units of score on BMI for women aged 18-24 years reported a reduced risk of breast cancer by 23 percent. With an increase in the exact same BMMI score, in the age range of 25-34 years the risk was reduced by 15% and in the age range of 35 to 44 years the risk of breast cancer decreased 13 percent lower. The risk of breast cancer decreased by 12% lower in the group of women aged 45-54 who also experienced an increase in BMI scores in the range of 5 units.
However, it is not known exactly where the BMI score indicates the risk of breast cancer begins to increase.
Doesn't mean that you may deliberately fatten your body to excess, you know!
They suspect that the mechanism of the occurrence of breast cancer in younger women is slightly different from the general theory, which has been explained in the subarticles above.
Researchers believe there are many factors that influence the relationship between a high BMI score and a lower risk of cancer in young women. One of them is the difference in the number of hormones, such as the hormone estrogen, growth hormone, and breast density.
However, the researchers strongly emphasize that the results of this study were not published as support for women to deliberately over-add weight to avoid cancer. The potential for long-term health problems from obesity remains more dangerous than the benefits, which cannot even be ascertained.
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