Reye's Syndrome: A Liver and Brain Brain Disease

Reye's Syndrome: A Liver and Brain Brain Disease

Reye's Syndrome: A Liver and Brain Brain Disease


Reye's Syndrome: A Liver and Brain Brain Disease

Reye's syndrome is a matter of sudden brain damage and liver function that has no known cause. This syndrome usually occurs in children who are given aspirin when they suffer from chickenpox or flu. The use of aspirin to children is very dangerous, especially if giving it without permission from a doctor.

Most children and adolescents who have this syndrome can survive, even though they may experience a variety of permanent brain damage. Without proper diagnosis and treatment, this disease can be fatal in a few days. To find out more about Reye's syndrome, let's see more below.

Signs and symptoms of Reye's syndrome

In Reye's syndrome, the child's blood sugar level usually decreases while the ammonia level and acidity in the blood increases. At the same time, the liver can swell and cause fat buildup. Swelling can also occur in the brain, which can cause seizures and loss of consciousness. The signs and symptoms of Reye's syndrome usually appear around three to five days after the appearance of a viral infection, such as a cold or smallpox, or an upper respiratory infection, such as a cold.

Early signs and symptoms

For children aged 2 years, the first signs of Reye's syndrome may include:

  • Diarrhea
  • Breath fast

For children and adolescents, initial signs and symptoms include:

  • Continuous or continuous vomiting
  • Unusual lethargy or sleepiness

Additional signs and symptoms

When the condition progresses, signs and symptoms can become more serious, including:

  • Aggressive, irrational, or angry behavior
  • Confusion, disorientation, or hallucinations
  • Weakness or paralysis of the arms and legs.
  • Seizures
  • Excessive lethargy
  • Decreased level of consciousness

All signs and symptoms above require immediate medical attention.

Causes of Reye's syndrome

The exact cause of Reye's syndrome is unknown, although several factors may play a role in its development. Reye's syndrome seems to be triggered by using aspirin to treat cirus or infections, especially flu and smallpox, in children and adolescents who have impaired fatty acid oxidation.

Disorders of fatty acid oxidation are inherited metabolic disorders in which the body is unable to break down fatty acids, because enzymes have disappeared or are not working properly. A screening test is needed to determine if your child has the disorder.

In some cases, Reye's syndrome may be a metabolic condition that arises due to viral diseases. Exposure to certain toxins, such as insecticides, herbicides, and thinners, can also contribute to this syndrome.

How to treat Reye's syndrome

People with Reye's syndrome are usually hospitalized. Severe cases can be treated in the intensive care unit. Hospital staff will continue to monitor your child's blood pressure and other vital signs. Specific treatments may include:

  • Infusion fluid. Glucose and electrolyte solutions are given by intravenous route.
  • Diuretics. This drug can be used to reduce intracranial pressure and increase discharge through urine.
  • Medication to prevent bleeding. Bleeding due to abnormalities of the day requires treatment with vitamin K, plasma, and platelets.

How to prevent Reye's syndrome

Use aspirin carefully to children and adolescents. Although aspirin has been approved for use in children over 2 years of age, do not give aspirin to children and adolescents who have recently recovered from chickenpox or flu. This includes plain aspirin and drugs containing aspirin.

Some hospitals and medical facilities have carried out several checks on newborns to determine which older children have Reye's syndrome. Children who have impaired fatty acid oxidation should not take aspirin or products containing aspirin.

Always check the label before giving medicine to your child, including over-the-counter products and alternative or herbal medicines. Aspirin can also appear on some unexpected drugs, such as Alka-Seltzer. Sometimes, aspirin also comes under other names, such as acetylsalicylic acid, acetylsalicylate, salicylic acid, and salicylate.


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