12 of the World's Strangest and Rarest Diseases

12 of the World's Strangest and Rarest Diseases

12 of the World's Strangest and Rarest Diseases


12 of the World's Strangest and Rarest Diseases

When talking about strange diseases, which may sound familiar are elephant's feet or Zika. However, some of these lists are so rare that you might never have heard of them at all. In fact, the majority of these diseases have no treatment options and still confuse doctors all over the world

1. Persistent sexual arousal syndrome: stimulated endlessly

Passion and seconds to climax will usually only be felt during sex or masturbation. However, a handful of people can almost every time be on the verge of orgasm during their daily activities. For example when crossing the street or even waiting for a public bus. Even though. they do not experience or receive any sexual stimulation.

This continuous, aroused condition is called Persistent Sexual Arousal Syndrome (PSAS). PSAS can attack anyone regardless of age, gender, or sexual orientation. However, the cause is unknown until now.

Some scientists believe that nerve hypersensitivity in the genital organs can be one of the causes. Others suspect that the narrowing of the venous blood vessels in the pelvis to hormonal disorders is the cause.

2. Exploding head syndrome: "bomb blast" in the head

A loud noise wakes you up at night or surprises you until it jumps when you fall asleep? Though after the lyrics right-left, there is not one thing that causes noise. The loud noise came from inside your head.

Exploding Head Syndrome sounds like a scenario from a horror film, but this is actually a serious medical condition that affects thousands of people around the world. Symptoms of this disease are sleep disturbed by flashes of bright light, shortness of breath, increased heart rate, accompanied by sounds that sound like an exploding bomb, gun shots, cymbal collisions, or other versions of loud sounds in someone's head when trying to sleep. There are no symptoms of pain, swelling or other physical problems.

When the head "explodes", the situation is usually described as a brain shutdown process, similar to a dead computer. When the brain goes to sleep, the brain will "die" gradually, starting from the motor, hearing, and nerve aspects, followed by visuals - but then something is wrong in the process. Unfortunately, the drugs currently available are only able to reduce the volume of the explosion but don't actually stop the sound.

3. Progeria: 5 years old, looks like 80 years old

Generally, the symptoms of aging will begin to appear in middle age. But for children who have Progeria or Hutchinson-Gilford Progeria Syndrome 3, their physical appearance even looks like an 80-year-old elderly person even though his actual age hasn't turned two years. They have protruding eyes, a thin nose with a beak tip, thin lips, a small chin, and ears sticking out. Progeria is caused by genetic disability.

Even though they are mentally underage mentally, the physically progressive children will physically grow older just like the elderly. Starting from hair loss and thinning, graying, sagging and wrinkled skin here and there, suffering from joint pain, to bone loss.

Progreria is a rare life-threatening condition. There are only 48 children around the world who have managed to grow up with this condition. On average, children born with progeria will not survive beyond the age of 13. However, there is a family that has five children with this strange disease.

Progeria is deadly because many of these children also develop diseases that are usually associated with old age, such as heart disease and arthritis. They experience acute arterial hardening (arteriosclerosis) that starts in childhood, which triggers a heart attack or stroke at a very young age.

4. Stone Man’s disease: grows new bones in the body

Medically known as Fibrodysplasia Progressiva Ossificance (FOP), Stone Man's disease is one of the rarest, most painful and most disabling genetic conditions. Stone Man’s disease causes new bone growth to occur in place of muscles, tendons, ligaments, and other connective tissue that should not be overgrown with bone.

This strange disease is caused by a genetic mutation in the body's immune system to repair an injury. After injury, new bones will develop throughout the joint, limiting movement and forming a second skeleton. This condition makes the sufferer like a living mannequin that moves stiffly. Even the slightest trauma and injury, even injection marks, can cause bones to begin to grow.

Unfortunately, there is no effective treatment for this condition other than taking general painkillers. FOP occurs in one in two million people, but there are only 800 officially registered cases in the world.

5. Xeroderma Pigmentosum: vampire in the real world

Humans need sunlight to get vitamin D, but about 1 in 1 million people have xeroderma pigmentosum (XP) and are very sensitive to UV light. They must be completely protected from sunlight, or will experience extreme sunburn and severe skin damage.

Xeroderma pigmentosum (XP) is a subtype of a disorder known as porphyria. This condition is caused by a mutation of a rare enzyme that causes the skin to not recover itself as soon as it is damaged by exposure to UV radiation.

Symptoms usually first appear in early childhood, marked by severe blistering after only a few minutes of exposure. The eyes also become red, blurred, and irritated from UV exposure.

People with XP have a very high risk of developing skin cancer. Nearly half of all children who have XP will develop certain types of skin cancer at the age of 10 years. It is estimated that only one in 250,000 people in Europe and the United States have XP. Although there are several treatments available, the best prevention of severe skin damage is just staying in the dark and away from the sun, like a vampire.

6. Cotard's delusion: zombies in the real world

Cotard’s delusion aka Walking Corpse Syndrome is a rare mental disorder in which someone believes wholeheartedly that he is a zombie. They believe they are dead but half alive for reasons that do not make sense if we hear it. For example, he felt all the blood in his body was drained, his spirit was taken by the devil, or all of his organs had been stripped down.

Some people who suffer from this syndrome may also claim that they can smell their own flesh rot or feel maggots crawling on their skin. Others believe that they cannot die (because they are already dead, according to them).

Patients tend not to eat or bathe, and often spend time in the graveyard on the grounds that they want to blend in with their own "people".

This condition is most common among people with schizophrenia and people who have had severe head trauma. People who suffer from chronic sleep deprivation or suffer from psychosis after using amphetamine or cocaine also often show symptoms of Cotard's syndrome.

Cotard's delusion is thought to arise due to interference in the area of ​​the brain responsible for recognizing and connecting emotions with the face, including their own faces. This causes sufferers to experience dissociation when they see their body.

7. Alien Hand: Hands have their own life

Alien Hand Syndrome is a strange disease that makes the owner of the body completely unable to control the movements of his own hands. As if both of his hands have a life and a way of thinking that is separate from the body of the parent.

Researchers believe that this is a side effect of brain surgery or separation of the function of the brain lobe area. They found that the sufferers of the left and right brains were able to move independently of independent will. Sometimes, this syndrome can arise as a side effect that rarely occurs due to brain injury.

Alien Hand Syndrome there is no cure, but giving something to always hold hands is enough to make it stop moving temporarily. A study published by the journal Neurologist reports that Botox injections can help manage this syndrome.

8. Riley-Day Syndrome: super-immune to pain

Riley-Day syndrome, known as Familial dysautonomia or hereditary sensory neuropathy type 1 (HSN), is a rare genetic mutation that affects the autonomic nervous system connecting the brain and spinal cord to the muscles and cells that detect sensing sensations, such as touch, smell, and pain. The ability to feel pain and temperature is very disturbed, sometimes to the point where the individual really does not experience pain at all.

To really show signs of having a condition, however, the relevant genes must be lowered by both parents. This condition is also accompanied by frequent vomiting and difficulty swallowing.

Because HSN causes loss of sensation of pain, it is not new to sufferers to suffer random fractures and even necrosis, which results in the death of body tissue. People with HSN can even break their limbs or bite their tongue without feeling the slightest pain. Insensitivity to pain and pain can be life threatening in many situations, and because injuries and injuries may continue to be left untreated, boils and infections are common side effects.

9. Foreign Accent Syndrome: suddenly a thousand languages ​​are fluent

Accents can reveal a lot of information about the origin of a person, and many people who have tried speaking a foreign language other than their own mother tongue. However, some people can develop a condition that causes them to suddenly become fluent in foreign languages ​​and uncontrollable, even if they have never studied or visited the area of ​​origin of the language before. Often, different types of accents can "come out" at different times, or can be mixed together at one time.

Individuals who suffer from this condition not only change their accents and tone of voice, but also change the placement of the tongue when speaking. This rare, rare disease usually appears as a side effect after a stroke, severe migraine, or other brain injury. The only treatment available for this condition is extensive speech therapy to train the brain to speak in a certain way.

10. Hypertrichosis: werewolf

Another theme of horror films that "inspires" descriptions of this rare disease. Known as cognital lanuginose hypertrichosis, those born with this congenital condition have too fast hair growth and many are due to genetic mutations, which cover the body, including the face. This is the reason why hypertrichosis is also commonly referred to as the "werewolf" syndrome - without canine teeth and creepy sharp claws.

This condition can also be caused by side effects of anti-bald treatment, although some other cases occur without a known cause. Treatment options include the general method of hair removal, although even ordinary waxing and laser treatments do not provide long-lasting results.

Also Read:

  • 8 Types of Strange Allergies You Might Not Know
  • The 10 Most Horrifying and Deadly Rare Diseases in History
  • Are Eyes Yellow? Beware of Endophthalmitis, Infection That Can Make Blindness


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