Everyone must experience the aging process as we age. Indeed, no one can avoid this natural process. However, by understanding the process, it might be beneficial for humans to be able to intervene and prevent or slow down aging.
Researchers on anti aging see that the aging process is a disease that can and must be stopped. There is a recent examination that can help to measure how far the aging process is happening within us. Researchers have identified a natural chemical compound in urine. These compounds will appear in higher concentrations as you age.
Researchers say that these chemicals can function as markers or markers of your biological age, or how fast you age, compared to your age based on your date of birth.
Looking for signs of aging in the body
Researchers from West China Hospital at Sichuan University in Chengdu, China, are looking for a biomarker that can monitor how fast the aging process occurs in the human body. According to the theory of aging, the human body is aging due to free radicals. Free radicals are very reactive atoms or molecules that are produced due to the presence of oxygen, in a process called oxidation. If free radicals are not neutralized by antioxidants, free radicals can damage other cells.
Researchers say that the human body itself also produces free radicals that can cause oxidative damage to biomolecules in cells, such as DNA and RNA. As we get older, humans also experience increased oxidative damage resulting in an increase in biomarkers of markers or oxidative damage in the body.
The name of the chemical compound that can be a marker of this aging is 8-ox0-7,8-dihydroguanosine, shortened to 8-oxoGsn. This compound is produced continuously throughout life because it is a product of damage to RNA, an important molecule that interacts with DNA to activate gene expression and create proteins in the cell nucleus.
If the aging process is interpreted as a build-up of prolonged cell and tissue damage, then a compound that can measure RNA damage will be an appropriate marker for measuring aging.
In this latest study, experts looked at more than 1,200 men and women in China aged 2 to 90 years. They found that there was an increase in 8-oxoGsn levels with age. In other words, this marker level is higher in older people.
The level of 8-oxoGsn is not much different between men and women. But women who have gone through menopause show a higher 8-oxoGsn level. This may occur due to a decrease in the estrogen hormone that occurs during menopause, while estrogen is known to have an antioxidant effect.
What are the benefits of the discovery?
The aging process in humans occurs at different speeds for everyone. A 50-year-old man may have aged faster than a 65-year-old woman. That is why there are people who have gray or wrinkled at the age of 50, while there are also those who are 70 years old but still look young and fresh.
This is influenced by a combination of genetic factors and environmental factors. So, the discovery of an accurate marker to measure the level of aging is very useful to measure how quickly your body functions age or decrease.
Thus, a urine test that can detect how fast an individual is aging can also be used to measure the risk of age-related diseases. For example arthritis (arthritis), heart disease, and Alzheimer's disease. Doctors also can direct patients to take preventive measures for diseases, for example by changing their lifestyle to be healthier.
Unfortunately, further research is still needed to ascertain how accurately this urine test can be used as a reference for diagnosis. This technology is also still limited and must be further developed so that it is not yet available to lay people.
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